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Risk Factors of Ureteral Stenosis After Percutaneous Microwave Ablation of Renal Tumor, a Single-Center Experience

BACKGROUND: Ureteral stenosis after percutaneous microwave ablation (MWA) of renal tumor is a rare but severe complication, and its risk factors are not apparent. PURPOSE: This study aimed to investigate the risk factors for stenosis of ureter after MWA treatment of the renal tumor that is a rare co...

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Autores principales: Wu, Jiapeng, Yu, Jie, Cheng, Zhigang, Han, Zhiyu, Yu, Xiaoling, Li, Kai, Hu, Ping, Liu, Fangyi, Liang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531279/
https://www.ncbi.nlm.nih.gov/pubmed/33072565
http://dx.doi.org/10.3389/fonc.2020.521349
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author Wu, Jiapeng
Yu, Jie
Cheng, Zhigang
Han, Zhiyu
Yu, Xiaoling
Li, Kai
Hu, Ping
Liu, Fangyi
Liang, Ping
author_facet Wu, Jiapeng
Yu, Jie
Cheng, Zhigang
Han, Zhiyu
Yu, Xiaoling
Li, Kai
Hu, Ping
Liu, Fangyi
Liang, Ping
author_sort Wu, Jiapeng
collection PubMed
description BACKGROUND: Ureteral stenosis after percutaneous microwave ablation (MWA) of renal tumor is a rare but severe complication, and its risk factors are not apparent. PURPOSE: This study aimed to investigate the risk factors for stenosis of ureter after MWA treatment of the renal tumor that is a rare complication. MATERIALS AND METHODS: Data of 211 patients who underwent MWA for the treatment of renal tumor were retrospectively analyzed from September 2006 to August 2019. Demographic characteristics, clinical features, ablation parameters, and outcomes were analyzed to find out the potential risk factors of this complication. P < 0.05 is considered significant. RESULTS: Six of 211 patients developed ureter stenosis, and the rate of this complication is 2.84%. The median time of emergence of hydronephrosis was 226 (range, 3–390) days. Univariate analysis shows the distance between ureter and tumor (P = 0.225) or ablation zone (P = 0.089) is not related to this complication. Postoperative urine routine (red blood cell, P = 0.001; white blood cell, P = 0.035) and R.E.N.A.L. score (P < 0.001) is related to this complication. But after multivariate logistic analysis, only R.E.N.A.L. score (P = 0.004) is associated with this complication. The location and growth pattern of tumor and the energy of ablation were not related to this complication independently. CONCLUSION: The stenosis of the ureter after MWA of renal tumor is not associated with the tumor size, location, or the distance between the ureter and tumor and ablation site independently. But R.E.N.A.L. score is associated with ureter stenosis after MWA for the treatment of renal tumor, which combines the information of location, depth, and size of tumor. Preoperative evaluation of the tumor is necessary for avoiding ureter stenosis. Further studies should focus on these risk factors of this complication.
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spelling pubmed-75312792020-10-17 Risk Factors of Ureteral Stenosis After Percutaneous Microwave Ablation of Renal Tumor, a Single-Center Experience Wu, Jiapeng Yu, Jie Cheng, Zhigang Han, Zhiyu Yu, Xiaoling Li, Kai Hu, Ping Liu, Fangyi Liang, Ping Front Oncol Oncology BACKGROUND: Ureteral stenosis after percutaneous microwave ablation (MWA) of renal tumor is a rare but severe complication, and its risk factors are not apparent. PURPOSE: This study aimed to investigate the risk factors for stenosis of ureter after MWA treatment of the renal tumor that is a rare complication. MATERIALS AND METHODS: Data of 211 patients who underwent MWA for the treatment of renal tumor were retrospectively analyzed from September 2006 to August 2019. Demographic characteristics, clinical features, ablation parameters, and outcomes were analyzed to find out the potential risk factors of this complication. P < 0.05 is considered significant. RESULTS: Six of 211 patients developed ureter stenosis, and the rate of this complication is 2.84%. The median time of emergence of hydronephrosis was 226 (range, 3–390) days. Univariate analysis shows the distance between ureter and tumor (P = 0.225) or ablation zone (P = 0.089) is not related to this complication. Postoperative urine routine (red blood cell, P = 0.001; white blood cell, P = 0.035) and R.E.N.A.L. score (P < 0.001) is related to this complication. But after multivariate logistic analysis, only R.E.N.A.L. score (P = 0.004) is associated with this complication. The location and growth pattern of tumor and the energy of ablation were not related to this complication independently. CONCLUSION: The stenosis of the ureter after MWA of renal tumor is not associated with the tumor size, location, or the distance between the ureter and tumor and ablation site independently. But R.E.N.A.L. score is associated with ureter stenosis after MWA for the treatment of renal tumor, which combines the information of location, depth, and size of tumor. Preoperative evaluation of the tumor is necessary for avoiding ureter stenosis. Further studies should focus on these risk factors of this complication. Frontiers Media S.A. 2020-09-18 /pmc/articles/PMC7531279/ /pubmed/33072565 http://dx.doi.org/10.3389/fonc.2020.521349 Text en Copyright © 2020 Wu, Yu, Cheng, Han, Yu, Li, Hu, Liu and Liang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Wu, Jiapeng
Yu, Jie
Cheng, Zhigang
Han, Zhiyu
Yu, Xiaoling
Li, Kai
Hu, Ping
Liu, Fangyi
Liang, Ping
Risk Factors of Ureteral Stenosis After Percutaneous Microwave Ablation of Renal Tumor, a Single-Center Experience
title Risk Factors of Ureteral Stenosis After Percutaneous Microwave Ablation of Renal Tumor, a Single-Center Experience
title_full Risk Factors of Ureteral Stenosis After Percutaneous Microwave Ablation of Renal Tumor, a Single-Center Experience
title_fullStr Risk Factors of Ureteral Stenosis After Percutaneous Microwave Ablation of Renal Tumor, a Single-Center Experience
title_full_unstemmed Risk Factors of Ureteral Stenosis After Percutaneous Microwave Ablation of Renal Tumor, a Single-Center Experience
title_short Risk Factors of Ureteral Stenosis After Percutaneous Microwave Ablation of Renal Tumor, a Single-Center Experience
title_sort risk factors of ureteral stenosis after percutaneous microwave ablation of renal tumor, a single-center experience
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531279/
https://www.ncbi.nlm.nih.gov/pubmed/33072565
http://dx.doi.org/10.3389/fonc.2020.521349
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