(18)F-FBPA PET in Sarcoidosis: Comparison to Inflammation-Related Uptake on FDG PET

A 68-year-old man with sarcoidosis showed high (18)F-FDG uptake in the mediastinal and hilar lymph nodes on (18)F-FDG PET, suggesting active inflammation. (18)F-fluoro-boronophenylalanine (FBPA) PET showed no significant uptake in the mediastinal and hilar lymph nodes, suggesting its cancer specific...

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Autores principales: Watabe, Tadashi, Shimamoto, Hiroaki, Naka, Sadahiro, Kamiya, Takashi, Murakami, Shumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531499/
https://www.ncbi.nlm.nih.gov/pubmed/32969900
http://dx.doi.org/10.1097/RLU.0000000000003274
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author Watabe, Tadashi
Shimamoto, Hiroaki
Naka, Sadahiro
Kamiya, Takashi
Murakami, Shumei
author_facet Watabe, Tadashi
Shimamoto, Hiroaki
Naka, Sadahiro
Kamiya, Takashi
Murakami, Shumei
author_sort Watabe, Tadashi
collection PubMed
description A 68-year-old man with sarcoidosis showed high (18)F-FDG uptake in the mediastinal and hilar lymph nodes on (18)F-FDG PET, suggesting active inflammation. (18)F-fluoro-boronophenylalanine (FBPA) PET showed no significant uptake in the mediastinal and hilar lymph nodes, suggesting its cancer specificity as a substrate of l-type amino acid transporter 1. (18)F-fluoro-boronophenylalanine PET can be used for precise evaluation in oncology when the differentiation between inflammation and metastasis is inconclusive on (18)F-FDG PET.
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spelling pubmed-75314992020-10-14 (18)F-FBPA PET in Sarcoidosis: Comparison to Inflammation-Related Uptake on FDG PET Watabe, Tadashi Shimamoto, Hiroaki Naka, Sadahiro Kamiya, Takashi Murakami, Shumei Clin Nucl Med Interesting Images A 68-year-old man with sarcoidosis showed high (18)F-FDG uptake in the mediastinal and hilar lymph nodes on (18)F-FDG PET, suggesting active inflammation. (18)F-fluoro-boronophenylalanine (FBPA) PET showed no significant uptake in the mediastinal and hilar lymph nodes, suggesting its cancer specificity as a substrate of l-type amino acid transporter 1. (18)F-fluoro-boronophenylalanine PET can be used for precise evaluation in oncology when the differentiation between inflammation and metastasis is inconclusive on (18)F-FDG PET. Lippincott Williams & Wilkins 2020-11 2020-09-23 /pmc/articles/PMC7531499/ /pubmed/32969900 http://dx.doi.org/10.1097/RLU.0000000000003274 Text en Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Interesting Images
Watabe, Tadashi
Shimamoto, Hiroaki
Naka, Sadahiro
Kamiya, Takashi
Murakami, Shumei
(18)F-FBPA PET in Sarcoidosis: Comparison to Inflammation-Related Uptake on FDG PET
title (18)F-FBPA PET in Sarcoidosis: Comparison to Inflammation-Related Uptake on FDG PET
title_full (18)F-FBPA PET in Sarcoidosis: Comparison to Inflammation-Related Uptake on FDG PET
title_fullStr (18)F-FBPA PET in Sarcoidosis: Comparison to Inflammation-Related Uptake on FDG PET
title_full_unstemmed (18)F-FBPA PET in Sarcoidosis: Comparison to Inflammation-Related Uptake on FDG PET
title_short (18)F-FBPA PET in Sarcoidosis: Comparison to Inflammation-Related Uptake on FDG PET
title_sort (18)f-fbpa pet in sarcoidosis: comparison to inflammation-related uptake on fdg pet
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531499/
https://www.ncbi.nlm.nih.gov/pubmed/32969900
http://dx.doi.org/10.1097/RLU.0000000000003274
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