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Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions

Monoclonal antibodies are a class of biotherapeutics used for an increasing variety of disorders, including cancer, autoimmune, neurodegenerative, and viral diseases. Besides their antigen specificity, therapeutic use also mandates control of their solution interactions and colloidal properties in o...

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Detalles Bibliográficos
Autores principales: Chaturvedi, Sumit K., Parupudi, Arun, Juul-Madsen, Kristian, Nguyen, Ai, Vorup-Jensen, Thomas, Dragulin-Otto, Sonia, Zhao, Huaying, Esfandiary, Reza, Schuck, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531506/
https://www.ncbi.nlm.nih.gov/pubmed/32887536
http://dx.doi.org/10.1080/19420862.2020.1810488

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