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Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions
Monoclonal antibodies are a class of biotherapeutics used for an increasing variety of disorders, including cancer, autoimmune, neurodegenerative, and viral diseases. Besides their antigen specificity, therapeutic use also mandates control of their solution interactions and colloidal properties in o...
Autores principales: | Chaturvedi, Sumit K., Parupudi, Arun, Juul-Madsen, Kristian, Nguyen, Ai, Vorup-Jensen, Thomas, Dragulin-Otto, Sonia, Zhao, Huaying, Esfandiary, Reza, Schuck, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531506/ https://www.ncbi.nlm.nih.gov/pubmed/32887536 http://dx.doi.org/10.1080/19420862.2020.1810488 |
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