Cargando…

Enabling speed to clinic for monoclonal antibody programs using a pool of clones for IND-enabling toxicity studies

The importance of speed to clinic for medicines that may address unmet medical needs puts pressure on product development timelines. Historically, both toxicology and first-in-human clinical materials are generated using the same clonal-derived cells to ensure safety and minimize any development ris...

Descripción completa

Detalles Bibliográficos
Autores principales: Bolisetty, Parimala, Tremml, Gabi, Xu, Sen, Khetan, Anurag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531531/
https://www.ncbi.nlm.nih.gov/pubmed/32449878
http://dx.doi.org/10.1080/19420862.2020.1763727

Ejemplares similares