Mechanistic Insights Into the Anticancer Properties of the Auranofin Analog Au(PEt(3))I: A Theoretical and Experimental Study

Au(PEt(3))I (AF-I hereafter), the iodide analog of the FDA-approved drug auranofin (AF hereafter), is a promising anticancer agent that produces its pharmacological effects through interaction with non-genomic targets such as the thioredoxin reductase system. AF-I is endowed with a very favorable bi...

Descripción completa

Detalles Bibliográficos
Autores principales: Tolbatov, Iogann, Cirri, Damiano, Marchetti, Lorella, Marrone, Alessandro, Coletti, Cecilia, Re, Nazzareno, La Mendola, Diego, Messori, Luigi, Marzo, Tiziano, Gabbiani, Chiara, Pratesi, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531625/
https://www.ncbi.nlm.nih.gov/pubmed/33195032
http://dx.doi.org/10.3389/fchem.2020.00812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531625/
https://www.ncbi.nlm.nih.gov/pubmed/33195032
http://dx.doi.org/10.3389/fchem.2020.00812

Ejemplares similares