Depletion and activation of mucosal CD4 T cells in HIV infected women with HPV-associated lesions of the cervix uteri

BACKGROUND: The burden of HPV-associated premalignant and malignant cervical lesions remains high in HIV+ women even under ART treatment. In order to identify possible underlying pathophysiologic mechanisms, we studied activation and HIV co-receptor expression in cervical T-cell populations in relat...

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Detalles Bibliográficos
Autores principales: Mbuya, Wilbert, Mcharo, Ruby, Mhizde, Jacklina, Mnkai, Jonathan, Mahenge, Anifrid, Mwakatima, Maria, Mwalongo, Wolfram, Chiwerengo, Nhamo, Hölscher, Michael, Lennemann, Tessa, Saathoff, Elmar, Rwegoshora, France, Torres, Liset, Kroidl, Arne, Geldmacher, Christof, Held, Kathrin, Chachage, Mkunde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531815/
https://www.ncbi.nlm.nih.gov/pubmed/33007050
http://dx.doi.org/10.1371/journal.pone.0240154

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