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Modeling the activation of the alternative complement pathway and its effects on hemolysis in health and disease

The complement system is a powerful mechanism of innate immunity poised to eliminate foreign cells and pathogens. It is an intricate network of >35 proteins, which, once activated, leads to the tagging of the surface to be eliminated, produces potent chemoattractants to recruit immune cells, and...

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Detalles Bibliográficos
Autores principales: Caruso, Antonello, Vollmer, Jannik, Machacek, Matthias, Kortvely, Elod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531836/
https://www.ncbi.nlm.nih.gov/pubmed/33006965
http://dx.doi.org/10.1371/journal.pcbi.1008139