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The transcriptional elongation rate regulates alternative polyadenylation in yeast
Yeast cells undergoing the diauxic response show a striking upstream shift in poly(A) site utilization, with increased use of ORF-proximal poly(A) sites resulting in shorter 3’ mRNA isoforms for most genes. This altered poly(A) pattern is extremely similar to that observed in cells containing Pol II...
Autores principales: | Geisberg, Joseph V, Moqtaderi, Zarmik, Struhl, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532003/ https://www.ncbi.nlm.nih.gov/pubmed/32845240 http://dx.doi.org/10.7554/eLife.59810 |
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