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Splenic marginal zone lymphoma: a case report and literature review
BACKGROUND: Splenic marginal zone lymphoma (SMZL) is a rare non-Hodgkin lymphoma, and much little is known about its clinical characteristics and management strategies. Here we present a case of SMZL and review relevant literature to provide a better recognition of this disease entity. CASE PRESENTA...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532117/ https://www.ncbi.nlm.nih.gov/pubmed/33004051 http://dx.doi.org/10.1186/s12957-020-02030-3 |
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author | Zhang, Shiyu Xuan, Zefeng Zhang, Liang Lu, Jiahua Song, Penghong Zheng, Shusen |
author_facet | Zhang, Shiyu Xuan, Zefeng Zhang, Liang Lu, Jiahua Song, Penghong Zheng, Shusen |
author_sort | Zhang, Shiyu |
collection | PubMed |
description | BACKGROUND: Splenic marginal zone lymphoma (SMZL) is a rare non-Hodgkin lymphoma, and much little is known about its clinical characteristics and management strategies. Here we present a case of SMZL and review relevant literature to provide a better recognition of this disease entity. CASE PRESENTATION: A 49-year-old Chinese female was admitted to our hospital with complaints of abdominal distension and acid reflux. Physical examinations and imaging investigations suggested the presence of splenomegaly. Laboratory workups revealed mildly reduced white blood cell count otherwise was not remarkable. The patient underwent splenectomy. Histological examination combined with immunohistochemical analysis of the resected spleen confirmed the diagnosis of SMZL. The patient recovered uneventfully during follow-ups. CONCLUSIONS: Due to the rarity and unspecific clinical features, SMZL is extremely challenging to be diagnosed preoperatively. Patients with SMZL are generally associated with favorable prognosis. Combining the staging characteristics of non-Hodgkin’s lymphoma and splenic primary lymphoma may assist in clinical staging management of SMZL. |
format | Online Article Text |
id | pubmed-7532117 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-75321172020-10-05 Splenic marginal zone lymphoma: a case report and literature review Zhang, Shiyu Xuan, Zefeng Zhang, Liang Lu, Jiahua Song, Penghong Zheng, Shusen World J Surg Oncol Case Report BACKGROUND: Splenic marginal zone lymphoma (SMZL) is a rare non-Hodgkin lymphoma, and much little is known about its clinical characteristics and management strategies. Here we present a case of SMZL and review relevant literature to provide a better recognition of this disease entity. CASE PRESENTATION: A 49-year-old Chinese female was admitted to our hospital with complaints of abdominal distension and acid reflux. Physical examinations and imaging investigations suggested the presence of splenomegaly. Laboratory workups revealed mildly reduced white blood cell count otherwise was not remarkable. The patient underwent splenectomy. Histological examination combined with immunohistochemical analysis of the resected spleen confirmed the diagnosis of SMZL. The patient recovered uneventfully during follow-ups. CONCLUSIONS: Due to the rarity and unspecific clinical features, SMZL is extremely challenging to be diagnosed preoperatively. Patients with SMZL are generally associated with favorable prognosis. Combining the staging characteristics of non-Hodgkin’s lymphoma and splenic primary lymphoma may assist in clinical staging management of SMZL. BioMed Central 2020-10-01 /pmc/articles/PMC7532117/ /pubmed/33004051 http://dx.doi.org/10.1186/s12957-020-02030-3 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Zhang, Shiyu Xuan, Zefeng Zhang, Liang Lu, Jiahua Song, Penghong Zheng, Shusen Splenic marginal zone lymphoma: a case report and literature review |
title | Splenic marginal zone lymphoma: a case report and literature review |
title_full | Splenic marginal zone lymphoma: a case report and literature review |
title_fullStr | Splenic marginal zone lymphoma: a case report and literature review |
title_full_unstemmed | Splenic marginal zone lymphoma: a case report and literature review |
title_short | Splenic marginal zone lymphoma: a case report and literature review |
title_sort | splenic marginal zone lymphoma: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532117/ https://www.ncbi.nlm.nih.gov/pubmed/33004051 http://dx.doi.org/10.1186/s12957-020-02030-3 |
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