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Lysosomal Hydrolase Cathepsin D Non-proteolytically Modulates Dendritic Morphology in Drosophila
The main lysosomal protease cathepsin D (cathD) is essential for maintaining tissue homeostasis via its degradative function, and its loss leads to ceroid accumulation in the mammalian nervous system, which results in progressive neurodegeneration. Increasing evidence implies non-proteolytic roles o...
Autores principales: | Zhang, Ting, Cheng, Daxiao, Wu, Cunjin, Wang, Xingyue, Ke, Qiang, Lou, Huifang, Zhu, Liya, Wang, Xiao-Dong, Duan, Shumin, Liu, Yi-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532236/ https://www.ncbi.nlm.nih.gov/pubmed/32170568 http://dx.doi.org/10.1007/s12264-020-00479-6 |
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