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Association of the rs562556 PCSK9 Gene Polymorphism with Reduced Mortality in Severe Malaria among Malian Children

Recent evidence suggests that proprotein convertase subtilisin/kexin type 9 (PCSK9), a downmodulator of cellular uptake of blood cholesterol, also negatively impacts host immune response to microbial infection. In this study, we investigated whether carrying the loss-of-function (LOF) rs562556 (c.14...

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Detalles Bibliográficos
Autores principales: Fedoryak, Olesya, Arama, Charles, Diarra, Issa, Kouriba, Bouréma, Chrétien, Michel, Mbikay, Majambu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532394/
https://www.ncbi.nlm.nih.gov/pubmed/33029265
http://dx.doi.org/10.1155/2020/9340480