Metformin reverses the drug resistance of cisplatin in irradiated CNE-1 human nasopharyngeal carcinoma cells through PECAM-1 mediated MRPs down-regulation

Objective: To explore a way to reverse the drug resistance for irradiated CNE-1 human nasopharyngeal carcinoma cells and try to develop a new high efficacy with low toxicity therapeutic approach. Methods: 300 Gy irradiated the CNE-1 human nasopharyngeal carcinoma cells, and then treated with single-...

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Detalles Bibliográficos
Autores principales: Sun, Yingming, Chen, Xiaochuan, Zhou, Yajuan, Qiu, Sufang, Wu, Yongyang, Xie, Min, Zhu, Guofang, Liang, Shanshan, Li, Heming, Zhou, Dong, Ju, Zaishuang, Wang, Fuguang, Han, Fang, Wang, Zhe, Wang, Ruoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532475/
https://www.ncbi.nlm.nih.gov/pubmed/33029084
http://dx.doi.org/10.7150/ijms.48635

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