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Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer’s disease mouse model with suppression of glymphatic clearance

BACKGROUND: Soluble beta-amyloid (Aβ) can be cleared from the brain through various mechanisms including enzymatic degradation, glial cell phagocytosis, transport across the blood-brain barrier, and glymphatic clearance. However, the relative contribution of each clearance system and their compensat...

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Detalles Bibliográficos
Autores principales:	Feng, Weixi, Zhang, Yanli, Wang, Ze, Xu, Hanrong, Wu, Ting, Marshall, Charles, Gao, Junying, Xiao, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532614/ https://www.ncbi.nlm.nih.gov/pubmed/33008458 http://dx.doi.org/10.1186/s13195-020-00688-1

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