Pharmacological inhibition of mTORC1 increases CCKBR-specific tumor uptake of radiolabeled minigastrin analogue [(177)Lu]Lu-PP-F11N

Rationale: A high tumor-to-healthy-tissue uptake ratio of radiolabeled ligands is an essential prerequisite for safe and effective peptide receptor radionuclide therapy (PRRT). In the present study, we searched for novel opportunities to increase tumor-specific uptake of the radiolabeled minigastrin...

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Detalles Bibliográficos
Autores principales: Grzmil, Michal, Qin, Yun, Schleuniger, Carina, Frank, Stephan, Imobersteg, Stefan, Blanc, Alain, Spillmann, Martin, Berger, Philipp, Schibli, Roger, Behe, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532663/
https://www.ncbi.nlm.nih.gov/pubmed/33042258
http://dx.doi.org/10.7150/thno.45440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532663/
https://www.ncbi.nlm.nih.gov/pubmed/33042258
http://dx.doi.org/10.7150/thno.45440

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