Synthesis and preliminary studies of (11)C-labeled tetrahydro-1,7-naphthyridine-2-carboxamides for PET imaging of metabotropic glutamate receptor 2

Selective modulation of metabotropic glutamate receptor 2 (mGlu(2)) represents a novel therapeutic approach for treating brain disorders, including schizophrenia, depression, Parkinson's disease (PD), Alzheimer's disease (AD), drug abuse and addiction. Imaging mGlu(2) using positron emissi...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaofei, Zhang, Yiding, Chen, Zhen, Shao, Tuo, Van, Richard, Kumata, Katsushi, Deng, Xiaoyun, Fu, Hualong, Yamasaki, Tomoteru, Rong, Jian, Hu, Kuan, Hatori, Akiko, Xie, Lin, Yu, Qingzhen, Ye, Weijian, Xu, Hao, Sheffler, Douglas J., Cosford, Nicholas D. P., Shao, Yihan, Tang, Pingping, Wang, Lu, Zhang, Ming-Rong, Liang, Steven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532674/
https://www.ncbi.nlm.nih.gov/pubmed/33042277
http://dx.doi.org/10.7150/thno.42587

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