CRISPR-Sunspot: Imaging of endogenous low-abundance RNA at the single-molecule level in live cells

CRISPR/Cas-based mRNA imaging has been developed to labeling of high-abundance mRNAs. A lack of non-genetically encoded mRNA-tagged imaging tools has limited our ability to explore the functional distributions of endogenous low-abundance mRNAs in cells. Here, we developed a CRISPR-Sunspot method bas...

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Detalles Bibliográficos
Autores principales: Sun, Ning-He, Chen, Dan-Yang, Ye, Lu-Peng, Sheng, Gang, Gong, Jun-Jie, Chen, Bao-Hui, Lu, Ying-Mei, Han, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532675/
https://www.ncbi.nlm.nih.gov/pubmed/33042266
http://dx.doi.org/10.7150/thno.43094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532675/
https://www.ncbi.nlm.nih.gov/pubmed/33042266
http://dx.doi.org/10.7150/thno.43094

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