Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and toxicity in normal tissues

Most cancer patients receive chemotherapy at some stage of their treatment which makes improving the efficacy of cytotoxic drugs an ongoing and important goal. Despite large numbers of potent anti-cancer agents being developed, a major obstacle to clinical translation remains the inability to delive...

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Detalles Bibliográficos
Autores principales: Ingram, Nicola, McVeigh, Laura E., Abou-Saleh, Radwa H., Maynard, Juliana, Peyman, Sally A., McLaughlan, James R., Fairclough, Michael, Marston, Gemma, Valleley, Elizabeth M. A., Jimenez-Macias, Jorge L., Charalambous, Antonia, Townley, William, Haddrick, Malcolm, Wierzbicki, Antonia, Wright, Alexander, Volpato, Milène, Simpson, Peter B., Treanor, Darren E., Thomson, Neil H., Loadman, Paul M., Bushby, Richard J., Johnson, Benjamin R.G., Jones, Pamela F., Evans, J. Anthony, Freear, Steven, Markham, Alexander F., Evans, Stephen D., Coletta, P. Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532679/
https://www.ncbi.nlm.nih.gov/pubmed/33042265
http://dx.doi.org/10.7150/thno.49670

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