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Umbelliferone Inhibits Spermatogenic Defects and Testicular Injury in Lead-Intoxicated Rats by Suppressing Oxidative Stress and Inflammation, and Improving Nrf2/HO-1 Signaling

INTRODUCTION: Lead (Pb) is an environmental toxic metal that threatens human health. Umbelliferone (UMB) is a coumarin with known medicinal and protective properties against cytotoxicity. This study explored the ameliorative effect of UMB against Pb-induced testicular toxicity in rats, focusing on s...

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Detalles Bibliográficos
Autores principales: Alotaibi, Mohammed F, Al-Joufi, Fakhria, Abou Seif, Howida S, Alzoghaibi, Mohammed A, Djouhri, Laiche, Ahmeda, Ahmad F, Mahmoud, Ayman M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532898/
https://www.ncbi.nlm.nih.gov/pubmed/33061305
http://dx.doi.org/10.2147/DDDT.S265636

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