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Proanthocyanidins-Mediated Nrf2 Activation Ameliorates Glucocorticoid-Induced Oxidative Stress and Mitochondrial Dysfunction in Osteoblasts
The widespread use of therapeutic glucocorticoids has increased the frequency of glucocorticoid-induced osteoporosis (GIOP). One of the potential pathological processes of GIOP is an increased level of oxidative stress and mitochondrial dysfunction, which eventually leads to osteoblast apoptosis. Pr...
Autores principales: | Chen, Liang, Hu, Sun-Li, Xie, Jun, Yan, De-Yi, Weng, She-Ji, Tang, Jia-Hao, Wang, Bing-Zhang, Xie, Zhong-Jie, Wu, Zong-Yi, Yang, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533007/ https://www.ncbi.nlm.nih.gov/pubmed/33062149 http://dx.doi.org/10.1155/2020/9102012 |
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