Improving transgene expression and CRISPR‐Cas9 efficiency with molecular engineering‐based molecules

As a novel and robust gene‐editing tool, the Clustered Regularly Interspaced Short Palindromic Repeats CRISPR‐associated protein 9 (CRISPR‐Cas9) system has revolutionized gene therapy. Plasmid vector delivery is the most commonly used method for integrating the CRISPR‐Cas9 system into cells. However...

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Detalles Bibliográficos
Autores principales: Zhan, Hengji, Li, Aolin, Cai, Zhiming, Huang, Weiren, Liu, Yuchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533053/
https://www.ncbi.nlm.nih.gov/pubmed/33135339
http://dx.doi.org/10.1002/ctm2.194

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