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Predicting human pharmacokinetics from preclinical data: absorption

Predicting the rate and extent of oral absorption of drugs in humans has been a challenging task for new drug researchers. This tutorial reviews in vitro and PBPK methods reported in the past decades that are widely applied to predicting oral absorption in humans. The physicochemical property and pe...

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Detalles Bibliográficos
Autores principales: Yim, Dong-Seok, Choi, Suein, Bae, Soo Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533162/
https://www.ncbi.nlm.nih.gov/pubmed/33062626
http://dx.doi.org/10.12793/tcp.2020.28.e14

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