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Predicting human pharmacokinetics from preclinical data: absorption
Predicting the rate and extent of oral absorption of drugs in humans has been a challenging task for new drug researchers. This tutorial reviews in vitro and PBPK methods reported in the past decades that are widely applied to predicting oral absorption in humans. The physicochemical property and pe...
Autores principales: | Yim, Dong-Seok, Choi, Suein, Bae, Soo Hyeon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Clinical Pharmacology and Therapeutics
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533162/ https://www.ncbi.nlm.nih.gov/pubmed/33062626 http://dx.doi.org/10.12793/tcp.2020.28.e14 |
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