Design and tests of prospective property predictions for novel antimalarial 2-aminopropylaminoquinolones

There is a pressing need to improve the efficiency of drug development, and nowhere is that need more clear than in the case of neglected diseases like malaria. The peculiarities of pyrimidine metabolism in Plasmodium species make inhibition of dihydroorotate dehydrogenase (DHODH) an attractive targ...

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Detalles Bibliográficos
Autores principales: Clark, Robert D., Morris, Denise N., Chinigo, Gary, Lawless, Michael S., Prudhomme, Jacques, Le Roch, Karine G., Lafuente, Maria José, Ferrer, Santiago, Gamo, Francisco Javier, Gadwood, Robert, Woltosz, Walter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533260/
https://www.ncbi.nlm.nih.gov/pubmed/32833084
http://dx.doi.org/10.1007/s10822-020-00333-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533260/
https://www.ncbi.nlm.nih.gov/pubmed/32833084
http://dx.doi.org/10.1007/s10822-020-00333-x

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