Cargando…

A work-relatedness assessment in epidemiological case investigation of occupational cancers: I. Principles

It is important to identify the causal relationship between occupational exposure and the disease in the area of compensation because most cancers have long latent period. This review presents the principles that should be considered when evaluating the work-relatedness. We reviewed reports on occup...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Kihun, Kim, Jungwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Occupational & Environmental Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533286/
https://www.ncbi.nlm.nih.gov/pubmed/33072341
http://dx.doi.org/10.35371/aoem.2020.32.e30
_version_ 1783590099140739072
author Kim, Kihun
Kim, Jungwon
author_facet Kim, Kihun
Kim, Jungwon
author_sort Kim, Kihun
collection PubMed
description It is important to identify the causal relationship between occupational exposure and the disease in the area of compensation because most cancers have long latent period. This review presents the principles that should be considered when evaluating the work-relatedness. We reviewed reports on occupational cancers published by the International Agency for Research on Cancer, American Conference of Governmental Industrial Hygienists, National Toxicology Program, Environmental Protection Agency, European Union, which are the world's most prestigious organizations. In addition, we reviewed relevant papers and books published in Korea. The process is conducted in the order of cancer diagnosis, exposure assessment for carcinogens, and work-relatedness assessment. The probability of causation is determined stochastically rather than deterministically. There is no absolute standard for accreditation criteria and results may vary according to expert opinions and in each country or organization. Revealing the causal relationship of occupational cancers is a difficult process owing to inconsistency in relevant epidemiological studies, lack of well-established biological mechanisms, loss of objective occupational historical data, and other complexity of individual cases. Causation is unclear in many cases. Nevertheless, the data should be reviewed in detail for each case suspected of work-related cancers, and an assessment should be made through valid and plausible logic and literature evidences.
format Online
Article
Text
id pubmed-7533286
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Korean Society of Occupational & Environmental Medicine
record_format MEDLINE/PubMed
spelling pubmed-75332862020-10-16 A work-relatedness assessment in epidemiological case investigation of occupational cancers: I. Principles Kim, Kihun Kim, Jungwon Ann Occup Environ Med Review It is important to identify the causal relationship between occupational exposure and the disease in the area of compensation because most cancers have long latent period. This review presents the principles that should be considered when evaluating the work-relatedness. We reviewed reports on occupational cancers published by the International Agency for Research on Cancer, American Conference of Governmental Industrial Hygienists, National Toxicology Program, Environmental Protection Agency, European Union, which are the world's most prestigious organizations. In addition, we reviewed relevant papers and books published in Korea. The process is conducted in the order of cancer diagnosis, exposure assessment for carcinogens, and work-relatedness assessment. The probability of causation is determined stochastically rather than deterministically. There is no absolute standard for accreditation criteria and results may vary according to expert opinions and in each country or organization. Revealing the causal relationship of occupational cancers is a difficult process owing to inconsistency in relevant epidemiological studies, lack of well-established biological mechanisms, loss of objective occupational historical data, and other complexity of individual cases. Causation is unclear in many cases. Nevertheless, the data should be reviewed in detail for each case suspected of work-related cancers, and an assessment should be made through valid and plausible logic and literature evidences. Korean Society of Occupational & Environmental Medicine 2020-09-01 /pmc/articles/PMC7533286/ /pubmed/33072341 http://dx.doi.org/10.35371/aoem.2020.32.e30 Text en Copyright © 2020 Korean Society of Occupational & Environmental Medicine https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Kim, Kihun
Kim, Jungwon
A work-relatedness assessment in epidemiological case investigation of occupational cancers: I. Principles
title A work-relatedness assessment in epidemiological case investigation of occupational cancers: I. Principles
title_full A work-relatedness assessment in epidemiological case investigation of occupational cancers: I. Principles
title_fullStr A work-relatedness assessment in epidemiological case investigation of occupational cancers: I. Principles
title_full_unstemmed A work-relatedness assessment in epidemiological case investigation of occupational cancers: I. Principles
title_short A work-relatedness assessment in epidemiological case investigation of occupational cancers: I. Principles
title_sort work-relatedness assessment in epidemiological case investigation of occupational cancers: i. principles
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533286/
https://www.ncbi.nlm.nih.gov/pubmed/33072341
http://dx.doi.org/10.35371/aoem.2020.32.e30
work_keys_str_mv AT kimkihun aworkrelatednessassessmentinepidemiologicalcaseinvestigationofoccupationalcancersiprinciples
AT kimjungwon aworkrelatednessassessmentinepidemiologicalcaseinvestigationofoccupationalcancersiprinciples
AT kimkihun workrelatednessassessmentinepidemiologicalcaseinvestigationofoccupationalcancersiprinciples
AT kimjungwon workrelatednessassessmentinepidemiologicalcaseinvestigationofoccupationalcancersiprinciples