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Effects of tacrolimus on the TGF-β1/SMAD signaling pathway in paraquat-exposed rat alveolar type II epithelial cells

Paraquat is a highly toxic pesticide, which often causes pulmonary interstitial fibrosis after poisoning, and there is no specific antidote. At present, limited studies have reported that tacrolimus, as an immunosuppressant, can inhibit pulmonary fibrosis, but the specific mechanism remains unknown....

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Detalles Bibliográficos
Autores principales:	Ren, Yingli, Jian, Xiangdong, Zhang, Zhongchen, Ning, Qiong, Kan, Baotian, Kong, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533447/ https://www.ncbi.nlm.nih.gov/pubmed/33000210 http://dx.doi.org/10.3892/mmr.2020.11453

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