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Methylation status of CpG sites in the NOTCH4 promoter region regulates NOTCH4 expression in patients with tetralogy of Fallot

Tetralogy of Fallot (TOF) is the most common form of cyanotic congenital heart disease (CHD). Although a lower methylation level of whole genome has been demonstrated in TOF patients, little is known regarding the DNA methylation changes in specific gene and its associations with TOF development. NO...

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Detalles Bibliográficos
Autores principales: Zhu, Yanjie, Ye, Ming, Xu, Hongfei, Gu, Ruoyi, Ma, Xiaojing, Chen, Mingwu, Li, Xiaodi, Sheng, Wei, Huang, Guoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533461/
https://www.ncbi.nlm.nih.gov/pubmed/33000281
http://dx.doi.org/10.3892/mmr.2020.11535