ITCH regulates oxidative stress induced by high glucose through thioredoxin interacting protein in cultured human lens epithelial cells

Thioredoxin (Trx) is an important protein that controls oxidative damage in almost all eukaryotic cells. Trx interaction protein (Txnip) has been reported to negatively regulate the bioavailability of Trx and inhibit its biological function. The E3 ubiquitin ligase ITCH can specifically degrade Txni...

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Detalles Bibliográficos
Autores principales: Jiang, Lingfeng, Zhou, Wenkai, Lu, Bo, Yan, Qichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533507/
https://www.ncbi.nlm.nih.gov/pubmed/32901881
http://dx.doi.org/10.3892/mmr.2020.11499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533507/
https://www.ncbi.nlm.nih.gov/pubmed/32901881
http://dx.doi.org/10.3892/mmr.2020.11499

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