Progressive Encephalomyelitis With Rigidity and Myoclonus With Thymoma: A Case Report and Literature Review

Progressive encephalomyelitis with rigidity and myoclonus (PERM) is part of the variant type of the Stiff Person Syndrome (SPS) and is a rare neurological disease. We report here a patient with PERM who had thymoma and was positive for anti-glutamic acid decarboxylase (anti-GAD) antibodies. Her symp...

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Autores principales: Su, Yana, Cui, Li, Zhu, Mingqin, Liang, Yixuan, Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533529/
https://www.ncbi.nlm.nih.gov/pubmed/33071929
http://dx.doi.org/10.3389/fneur.2020.01017
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author Su, Yana
Cui, Li
Zhu, Mingqin
Liang, Yixuan
Zhang, Ying
author_facet Su, Yana
Cui, Li
Zhu, Mingqin
Liang, Yixuan
Zhang, Ying
author_sort Su, Yana
collection PubMed
description Progressive encephalomyelitis with rigidity and myoclonus (PERM) is part of the variant type of the Stiff Person Syndrome (SPS) and is a rare neurological disease. We report here a patient with PERM who had thymoma and was positive for anti-glutamic acid decarboxylase (anti-GAD) antibodies. Her symptoms improved after treatment with hormones and gamma globulin. We also summarized the literature review of patients with PERM accompanied by tumors reported.
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spelling pubmed-75335292020-10-16 Progressive Encephalomyelitis With Rigidity and Myoclonus With Thymoma: A Case Report and Literature Review Su, Yana Cui, Li Zhu, Mingqin Liang, Yixuan Zhang, Ying Front Neurol Neurology Progressive encephalomyelitis with rigidity and myoclonus (PERM) is part of the variant type of the Stiff Person Syndrome (SPS) and is a rare neurological disease. We report here a patient with PERM who had thymoma and was positive for anti-glutamic acid decarboxylase (anti-GAD) antibodies. Her symptoms improved after treatment with hormones and gamma globulin. We also summarized the literature review of patients with PERM accompanied by tumors reported. Frontiers Media S.A. 2020-09-18 /pmc/articles/PMC7533529/ /pubmed/33071929 http://dx.doi.org/10.3389/fneur.2020.01017 Text en Copyright © 2020 Su, Cui, Zhu, Liang and Zhang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Su, Yana
Cui, Li
Zhu, Mingqin
Liang, Yixuan
Zhang, Ying
Progressive Encephalomyelitis With Rigidity and Myoclonus With Thymoma: A Case Report and Literature Review
title Progressive Encephalomyelitis With Rigidity and Myoclonus With Thymoma: A Case Report and Literature Review
title_full Progressive Encephalomyelitis With Rigidity and Myoclonus With Thymoma: A Case Report and Literature Review
title_fullStr Progressive Encephalomyelitis With Rigidity and Myoclonus With Thymoma: A Case Report and Literature Review
title_full_unstemmed Progressive Encephalomyelitis With Rigidity and Myoclonus With Thymoma: A Case Report and Literature Review
title_short Progressive Encephalomyelitis With Rigidity and Myoclonus With Thymoma: A Case Report and Literature Review
title_sort progressive encephalomyelitis with rigidity and myoclonus with thymoma: a case report and literature review
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533529/
https://www.ncbi.nlm.nih.gov/pubmed/33071929
http://dx.doi.org/10.3389/fneur.2020.01017
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