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Treatment With Gemfibrozil Prevents the Progression of Chronic Kidney Disease in Obese Dahl Salt-Sensitive Rats

Recently, we reported that Dahl salt-sensitive leptin receptor mutant (SS(LepR)mutant) rats exhibit dyslipidemia and renal lipid accumulation independent of hyperglycemia that progresses to chronic kidney disease (CKD). Therefore, in the current study, we examined the effects of gemfibrozil, a lipid...

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Detalles Bibliográficos
Autores principales: Shields, Corbin A., Poudel, Bibek, McPherson, Kasi C., Brown, Andrea K., Ekperikpe, Ubong S., Browning, Evan, Sutton, Lamari, Cornelius, Denise C., Williams, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533555/
https://www.ncbi.nlm.nih.gov/pubmed/33071820
http://dx.doi.org/10.3389/fphys.2020.566403