Cargando…

Repurposing Ziyuglycoside II Against Colorectal Cancer via Orchestrating Apoptosis and Autophagy

Effective chemotherapy drugs for colorectal cancer remain a challenge. In this research, Ziyuglycoside II (Ziyu II), exhibits considerable antitumor activity against CRC cells both in vitro and in vivo. The results showed that Ziyu II induced apoptosis through the accumulation of reactive oxygen spe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bai, Can, Zhang, Zhe, Zhou, Li, Zhang, Huan-Yu, Chen, Yan, Tang, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533566/ https://www.ncbi.nlm.nih.gov/pubmed/33071789 http://dx.doi.org/10.3389/fphar.2020.576547

Ejemplares similares

A Sample and Sensitive HPLC-MS/MS Method for Simultaneous Determination of Ziyuglycoside I and Its Metabolite Ziyuglycoside II in Rat Pharmacokinetics
por: Li, Zhi-Feng, et al.
Publicado: (2018)

Ziyuglycoside II Inhibits the Growth of Human Breast Carcinoma MDA-MB-435 Cells via Cell Cycle Arrest and Induction of Apoptosis through the Mitochondria Dependent Pathway
por: Zhu, Xue, et al.
Publicado: (2013)

Isoalantolactone Induces Cell Cycle Arrest, Apoptosis and Autophagy in Colorectal Cancer Cells
por: Li, Junkui, et al.
Publicado: (2022)

Gold Nanoparticles Coated with SH-PEG-NH(2) and Loaded with Ziyuglycoside I for Promoting Autophagy in Hematopoietic Stem Cells
por: Xiong, Yongai, et al.
Publicado: (2023)

Anti-Diabetic and Hepato-Renal Protective Effects of Ziyuglycoside II Methyl Ester in Type 2 Diabetic Mice
por: Son, Dong Ju, et al.
Publicado: (2015)

Ziyuglycoside II-induced apoptosis in human gastric carcinoma BGC-823 cells by regulating Bax/Bcl-2 expression and activating caspase-3 pathway
por: Zhu, A.K., et al.
Publicado: (2013)

Repurposing Oxiconazole against Colorectal Cancer via PRDX2-mediated Autophagy Arrest
por: Shi, Jinyu, et al.
Publicado: (2022)

Drug repurposing in cancer neuroscience: From the viewpoint of the autophagy-mediated innervated niche
por: Shi, Jiayan, et al.
Publicado: (2022)

Repurposing phosphodiesterase-5 inhibitors as chemoadjuvants
por: Tiwari, Amit K., et al.
Publicado: (2013)

TPGS-Modified Long-Circulating Liposomes Loading Ziyuglycoside I for Enhanced Therapy of Myelosuppression
por: Song, Tingting, et al.
Publicado: (2021)

Hydroxyethyl Starch Curcumin Enhances Antiproliferative Effect of Curcumin Against HepG2 Cells via Apoptosis and Autophagy Induction
por: Jiang, Linhai, et al.
Publicado: (2021)

Fraxinellone Has Anticancer Activity by Inducing Osteosarcoma Cell Apoptosis via Promoting Excessive Autophagy Flux
por: He, Bin, et al.
Publicado: (2021)

Editorial: Autophagy in inflammation related diseases, volume II
por: Shao, Bo-Zong, et al.
Publicado: (2023)

Ang II Promotes Cardiac Autophagy and Hypertrophy via Orai1/STIM1
por: Zheng, Chang-Bo, et al.
Publicado: (2021)

Development and In Vivo Evaluation of Ziyuglycoside I–Loaded Self-Microemulsifying Formulation for Activity of Increasing Leukocyte
por: Xiong, Yongai, et al.
Publicado: (2019)

Capsaicin protects cardiomyocytes against lipopolysaccharide-induced damage via 14-3-3γ-mediated autophagy augmentation
por: Qiao, Yang, et al.
Publicado: (2021)

Paeonol Protects Against Myocardial Ischemia/Reperfusion-Induced Injury by Mediating Apoptosis and Autophagy Crosstalk
por: Tsai, Chin-Feng, et al.
Publicado: (2021)

A Ribonuclease Isolated from Wild Ganoderma Lucidum Suppressed Autophagy and Triggered Apoptosis in Colorectal Cancer Cells
por: Dan, Xiuli, et al.
Publicado: (2016)

Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells
por: Qu, Na, et al.
Publicado: (2022)

Inhibition of Autophagy Prevents Panax Notoginseng Saponins (PNS) Protection on Cardiac Myocytes Against Endoplasmic Reticulum (ER) Stress-Induced Mitochondrial Injury, Ca(2+) Homeostasis and Associated Apoptosis
por: Chen, Jun, et al.
Publicado: (2021)

Sempervirine Mediates Autophagy and Apoptosis via the Akt/mTOR Signaling Pathways in Glioma Cells
por: Li, Gaopan, et al.
Publicado: (2021)

Regulating Th17/Treg Balance Contributes to the Therapeutic Effect of Ziyuglycoside I on Collagen-Induced Arthritis
por: Wang, Manman, et al.
Publicado: (2022)

Repurposing Drugs, Ongoing Vaccine, and New Therapeutic Development Initiatives Against COVID-19
por: Saha, Rudra P., et al.
Publicado: (2020)

Icariin Activates Autophagy via Down-Regulation of the NF-κB Signaling-Mediated Apoptosis in Chondrocytes
por: Mi, Bobin, et al.
Publicado: (2018)

GM-CSF: Orchestrating the Pulmonary Response to Infection
por: McCormick, Thomas S., et al.
Publicado: (2022)

Repurposing of Bromocriptine for Cancer Therapy
por: Seo, Ean-Jeong, et al.
Publicado: (2018)

Repurposing antitussive benproperine phosphate against pancreatic cancer depends on autophagy arrest
por: Zhang, Huanyu, et al.
Publicado: (2020)

Bavachin Protects Human Aortic Smooth Muscle Cells Against β-Glycerophosphate-Mediated Vascular Calcification and Apoptosis via Activation of mTOR-Dependent Autophagy and Suppression of β-Catenin Signaling
por: He, Hu-Qiang, et al.
Publicado: (2019)

Melatonin Ameliorates Coxsackievirus B3-Induced Myocarditis by Regulating Apoptosis and Autophagy
por: Sang, Yimiao, et al.
Publicado: (2018)

Antitumor Effects of Trimethylellagic Acid Isolated From Sanguisorba officinalis L. on Colorectal Cancer via Angiogenesis Inhibition and Apoptosis Induction
por: Bai, Chongfei, et al.
Publicado: (2020)

Disulfiram in glioma: Literature review of drug repurposing
por: Zhong, Shiyu, et al.
Publicado: (2022)

Rhoifolin Ameliorates Osteoarthritis via Regulating Autophagy
por: Yan, Jiyuan, et al.
Publicado: (2021)

Pioglitazone Protects Against Renal Ischemia-Reperfusion Injury via the AMP-Activated Protein Kinase-Regulated Autophagy Pathway
por: Chen, Wenlin, et al.
Publicado: (2018)

Inflammation aggravated the hepatotoxicity of triptolide by oxidative stress, lipid metabolism disorder, autophagy, and apoptosis in zebrafish
por: Li, Chenqinyao, et al.
Publicado: (2022)

Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy
por: Ye, Jingxue, et al.
Publicado: (2020)

Five Constituents Contributed to the Psoraleae Fructus-Induced Hepatotoxicity via Mitochondrial Dysfunction and Apoptosis
por: Guo, Zhaojuan, et al.
Publicado: (2021)

Repurposing of Antibiotics: Sense or Non-sense
por: Talat, Absar, et al.
Publicado: (2022)

Repurposing Tranexamic Acid as an Anticancer Agent
por: Law, Mary E., et al.
Publicado: (2022)

Phytochemicals Mediate Autophagy Against Osteoarthritis by Maintaining Cartilage Homeostasis
por: Tian, Zheng, et al.
Publicado: (2021)

CAFs orchestrates tumor immune microenvironment—A new target in cancer therapy?
por: Zhang, Chunxue, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_81kmgf9ud61askeb765uq31jct