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Giant toxic multinodular goiter with dyspnea: A case report

INTRODUCTION: Toxic multinodular goiter (MNG) involves an enlarged thyroid gland, is a common cause of hyperthyroidism and when it is accompanied by obstructive symptoms such as dyspnea, it carries an indication for surgery. CASE PRESENTATION: We present a case of 47-year old female with multinodula...

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Autores principales: Alaguvelsamy, Sujeethra, Pal Singh, Sachender, Ramalingam, Ravi, Kombupalayam Komarappa Gounder, Ramalingam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533637/
https://www.ncbi.nlm.nih.gov/pubmed/32693233
http://dx.doi.org/10.1016/j.ijscr.2020.07.017
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author Alaguvelsamy, Sujeethra
Pal Singh, Sachender
Ramalingam, Ravi
Kombupalayam Komarappa Gounder, Ramalingam
author_facet Alaguvelsamy, Sujeethra
Pal Singh, Sachender
Ramalingam, Ravi
Kombupalayam Komarappa Gounder, Ramalingam
author_sort Alaguvelsamy, Sujeethra
collection PubMed
description INTRODUCTION: Toxic multinodular goiter (MNG) involves an enlarged thyroid gland, is a common cause of hyperthyroidism and when it is accompanied by obstructive symptoms such as dyspnea, it carries an indication for surgery. CASE PRESENTATION: We present a case of 47-year old female with multinodular goiter with a rapid increase in size within 2 years. She also reported palpitation, breathlessness on exertion, tachycardia and hand tremor. Computed tomography scan of the neck shows a gross enlargement of thyroid gland across both sides of the neck. The fine needle aspiration cytology and final histopathological examination were suggestive of MNG with adenomatous nodules and toxic changes respectively. A total thyroidectomy was performed and the gland was dissected successfully. DISCUSSION: Toxic MNG is most effectively treated by total thyroidectomy, which achieves complete diminution from symptoms. CONCLUSION: Surgery for huge goiter is challenging and one should be careful about difficult intubation, altered anatomy and adhesions to the surrounding structures. Recognizing and treating this kind of cases are important, as they constitute a preventable cause of mortality if timely diagnosed and treated.
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spelling pubmed-75336372020-10-07 Giant toxic multinodular goiter with dyspnea: A case report Alaguvelsamy, Sujeethra Pal Singh, Sachender Ramalingam, Ravi Kombupalayam Komarappa Gounder, Ramalingam Int J Surg Case Rep Case Report INTRODUCTION: Toxic multinodular goiter (MNG) involves an enlarged thyroid gland, is a common cause of hyperthyroidism and when it is accompanied by obstructive symptoms such as dyspnea, it carries an indication for surgery. CASE PRESENTATION: We present a case of 47-year old female with multinodular goiter with a rapid increase in size within 2 years. She also reported palpitation, breathlessness on exertion, tachycardia and hand tremor. Computed tomography scan of the neck shows a gross enlargement of thyroid gland across both sides of the neck. The fine needle aspiration cytology and final histopathological examination were suggestive of MNG with adenomatous nodules and toxic changes respectively. A total thyroidectomy was performed and the gland was dissected successfully. DISCUSSION: Toxic MNG is most effectively treated by total thyroidectomy, which achieves complete diminution from symptoms. CONCLUSION: Surgery for huge goiter is challenging and one should be careful about difficult intubation, altered anatomy and adhesions to the surrounding structures. Recognizing and treating this kind of cases are important, as they constitute a preventable cause of mortality if timely diagnosed and treated. Elsevier 2020-07-15 /pmc/articles/PMC7533637/ /pubmed/32693233 http://dx.doi.org/10.1016/j.ijscr.2020.07.017 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Alaguvelsamy, Sujeethra
Pal Singh, Sachender
Ramalingam, Ravi
Kombupalayam Komarappa Gounder, Ramalingam
Giant toxic multinodular goiter with dyspnea: A case report
title Giant toxic multinodular goiter with dyspnea: A case report
title_full Giant toxic multinodular goiter with dyspnea: A case report
title_fullStr Giant toxic multinodular goiter with dyspnea: A case report
title_full_unstemmed Giant toxic multinodular goiter with dyspnea: A case report
title_short Giant toxic multinodular goiter with dyspnea: A case report
title_sort giant toxic multinodular goiter with dyspnea: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533637/
https://www.ncbi.nlm.nih.gov/pubmed/32693233
http://dx.doi.org/10.1016/j.ijscr.2020.07.017
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