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Synthesis of artificial substrate based on inhibitor for detecting LSD1 activity
Lysine methylation is one of the most important modification, which is regulated by histone lysine methyltransferases and histone lysine demethylases. Lysine-specific demethylase 1 (LSD1) specifically demethylates mono- and dimethyl-lysine on histone H3 (H3K4Me/Me(2), H3K9Me/Me(2)) to control chroma...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
the Society for Free Radical Research Japan
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533851/ https://www.ncbi.nlm.nih.gov/pubmed/33041512 http://dx.doi.org/10.3164/jcbn.20-9 |