Synthesis of artificial substrate based on inhibitor for detecting LSD1 activity

Lysine methylation is one of the most important modification, which is regulated by histone lysine methyltransferases and histone lysine demethylases. Lysine-specific demethylase 1 (LSD1) specifically demethylates mono- and dimethyl-lysine on histone H3 (H3K4Me/Me(2), H3K9Me/Me(2)) to control chroma...

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Detalles Bibliográficos
Autores principales: Ohta, Yuhei, Kawaguchi, Mitsuyasu, Ieda, Naoya, Nakagawa, Hidehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533851/
https://www.ncbi.nlm.nih.gov/pubmed/33041512
http://dx.doi.org/10.3164/jcbn.20-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533851/
https://www.ncbi.nlm.nih.gov/pubmed/33041512
http://dx.doi.org/10.3164/jcbn.20-9

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