Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2

Sphingolipid dysregulation is often associated with insulin resistance, while the enzymes controlling sphingolipid metabolism are emerging as therapeutic targets for improving insulin sensitivity. We report herein that sphingosine kinase 2 (SphK2), a key enzyme in sphingolipid catabolism, plays a cr...

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Detalles Bibliográficos
Autores principales: Aji, Gulibositan, Huang, Yu, Ng, Mei Li, Wang, Wei, Lan, Tian, Li, Min, Li, Yufei, Chen, Qi, Li, Rui, Yan, Sishan, Tran, Collin, Burchfield, James G., Couttas, Timothy A., Chen, Jinbiao, Chung, Long Hoa, Liu, Da, Wadham, Carol, Hogg, Philip J., Gao, Xin, Vadas, Mathew A., Gamble, Jennifer R., Don, Anthony S., Xia, Pu, Qi, Yanfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533871/
https://www.ncbi.nlm.nih.gov/pubmed/32917816
http://dx.doi.org/10.1073/pnas.2007856117

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