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2-Hydroxyglutarate in Cancer Cells
Significance: Cancer cells are stabilized in an undifferentiated state similar to stem cells. This leads to profound modifications of their metabolism, which further modifies their genetics and epigenetics as malignancy progresses. Specific metabolites and enzymes may serve as clinical markers of ca...
Autor principal: | Ježek, Petr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533892/ https://www.ncbi.nlm.nih.gov/pubmed/31847543 http://dx.doi.org/10.1089/ars.2019.7902 |
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