Lymphocyte Activation Gene (LAG)-3 Is Associated With Mucosal Inflammation and Disease Activity in Ulcerative Colitis

BACKGROUND AND AIMS: Lymphocyte activation gene [LAG]-3 is an immune checkpoint and its expression identifies recently activated lymphocytes that may contribute to inflammation. We investigated the role of LAG-3 by analysing its expression and function in immune cells from blood and tissue of patien...

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Detalles Bibliográficos
Autores principales: Slevin, Stephanie M, Garner, Lucy C, Lahiff, Conor, Tan, Malcolm, Wang, Lai Mun, Ferry, Helen, Greenaway, Borgel, Lynch, Kate, Geremia, Alessandra, Hughes, Stephen, Leavens, Karen, Krull, David, Marks, Daniel J B, Nevin, Katherine, Page, Kevin, Srinivasan, Naren, Tarzi, Ruth, Klenerman, Paul, Travis, Simon, Arancibia-Cárcamo, Carolina V, Keshav, Satish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533903/
https://www.ncbi.nlm.nih.gov/pubmed/32179884
http://dx.doi.org/10.1093/ecco-jcc/jjaa054

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