Cargando…

Phosphorylation of CREB-Specific Coactivator CRTC2 at Ser238 Promotes Proliferation, Migration, and Invasion of Colorectal Cancer Cells

cAMP response element binding protein (CREB)-regulated transcription coactivator 2 (CRTC2), a member of the novel CRTC family of transcriptional coactivators that activates basic leucine zipper transcription factors, including CREB, is overexpressed in many carcinomas, including colon cancer. Phosph...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yi, Liu, Qian, Zhang, Hanshuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533939/ https://www.ncbi.nlm.nih.gov/pubmed/33000695 http://dx.doi.org/10.1177/1533033820962111

Ejemplares similares

The CREB Coactivator CRTC2 Links Hepatic ER Stress and Fasting Gluconeogenesis
por: Wang, Yiguo, et al.
Publicado: (2009)

Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment
por: Sonntag, Tim, et al.
Publicado: (2018)

The CREB coactivator CRTC2 promotes oncogenesis in LKB1-mutant non–small cell lung cancer
por: Rodón, Laura, et al.
Publicado: (2019)

Involvement of CREB-regulated transcription coactivators (CRTC) in transcriptional activation of steroidogenic acute regulatory protein (Star) by ACTH
por: Smith, Lorna I.F., et al.
Publicado: (2020)

Activation and expression of endogenous CREB‐regulated transcription coactivators (CRTC) 1, 2 and 3 in the rat adrenal gland
por: Smith, Lorna I. F., et al.
Publicado: (2020)

Activation of the CREB Coactivator CRTC2 by Aberrant Mitogen Signaling promotes oncogenic functions in HPV16 positive head and neck cancer
por: Carper, Miranda B., et al.
Publicado: (2022)

Activation of the adipocyte CREB/CRTC pathway in obesity
por: Yoon, Young-Sil, et al.
Publicado: (2021)

Requirement of CRTC1 coactivator for hepatitis B virus transcription
por: Tang, Hei-Man Vincent, et al.
Publicado: (2014)

The CREB/CRTC2 Pathway Modulates Autoimmune Disease by Promoting Th17 Differentiation
por: Hernandez, Jeniffer B., et al.
Publicado: (2015)

CRTC1 transcriptional coactivator is required for hepatitis B virus gene expression and replication
por: Tang, Hei-Man Vincent, et al.
Publicado: (2014)

Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer
por: Komiya, Takefumi, et al.
Publicado: (2009)

Dependency of human and murine LKB1-inactivated lung cancer on aberrant CRTC-CREB activation
por: Zhou, Xin, et al.
Publicado: (2021)

The CRTC-CREB axis functions as a transcriptional sensor to protect against proteotoxic stress in Drosophila
por: Yin, Youjie, et al.
Publicado: (2022)

CRTC2 promotes non‐small cell lung cancer A549 migration and invasion in vitro
por: Shi, Shaoqing, et al.
Publicado: (2017)

Dipyridamole induces the phosphorylation of CREB to promote cancer cell proliferation
por: Abdelghany, Lina, et al.
Publicado: (2021)

Activation of Crtc2/Creb1 in skeletal muscle enhances weight loss during intermittent fasting
por: Bruno, Nelson E., et al.
Publicado: (2021)

Diet change and exercise enhance protein expression of CREB, CRTC 2 and lipolitic enzymes in adipocytes of obese mice
por: Woo, Jinhee, et al.
Publicado: (2016)

Glucocorticoids Alter CRTC-CREB Signaling in Muscle Cells: Impact on PGC-1α Expression and Atrophy Markers
por: Rahnert, Jill A., et al.
Publicado: (2016)

Salt-inducible kinase 1 regulates bone anabolism via the CRTC1–CREB–Id1 axis
por: Kim, Min Kyung, et al.
Publicado: (2019)

Nuclear receptor coactivator 6 (NCoA6) promotes cell proliferation, migration, and invasion in pancreatic cancer
por: Wang, Xin, et al.
Publicado: (2023)

A propolis-derived small molecule ameliorates metabolic syndrome in obese mice by targeting the CREB/CRTC2 transcriptional complex
por: Chen, Yaqiong, et al.
Publicado: (2022)

Anabolic and Pro-metabolic Functions of CREB-CRTC in Skeletal Muscle: Advantages and Obstacles for Type 2 Diabetes and Cancer Cachexia
por: Berdeaux, Rebecca, et al.
Publicado: (2019)

CRTC2 activates the epithelial–mesenchymal transition of diabetic kidney disease through the CREB-Smad2/3 pathway
por: Li, Yujie, et al.
Publicado: (2023)

MSK1 promotes cell proliferation and metastasis in uveal melanoma by phosphorylating CREB
por: Li, Jianchang, et al.
Publicado: (2019)

CREB-Regulated Transcriptional Coactivator 2 Proteome Landscape is Modulated by SREBF1
por: Lim, Jae Min, et al.
Publicado: (2023)

Artepillin C Time−Dependently Alleviates Metabolic Syndrome in Obese Mice by Regulating CREB/CRTC2−BMAL1 Signaling
por: Wang, Lei, et al.
Publicado: (2023)

Proline hydroxylation of CREB-regulated transcriptional coactivator 2 controls hepatic glucose metabolism
por: Xue, Yaqian, et al.
Publicado: (2023)

CREB-regulated transcription coactivator 1 enhances CREB-dependent gene expression in spinal cord to maintain the bone cancer pain in mice
por: Liang, Ying, et al.
Publicado: (2016)

Leptin recruits Creb-regulated transcriptional coactivator 1 to improve hyperglycemia in insulin-deficient diabetes
por: Kim, Geun Hyang, et al.
Publicado: (2014)

JNK suppresses melanogenesis by interfering with CREB-regulated transcription coactivator 3-dependent MITF expression
por: Kim, Ji-Hye, et al.
Publicado: (2020)

New Insights Into the Pivotal Role of CREB-Regulated Transcription Coactivator 1 in Depression and Comorbid Obesity
por: Rossetti, Clara, et al.
Publicado: (2022)

ERK2-Mediated Phosphorylation of Transcriptional Coactivator Binding Protein PIMT/NCoA6IP at Ser(298) Augments Hepatic Gluconeogenesis
por: Kapadia, Bandish, et al.
Publicado: (2013)

The Selective SIK2 Inhibitor ARN-3236 Produces Strong Antidepressant-Like Efficacy in Mice via the Hippocampal CRTC1-CREB-BDNF Pathway
por: Liu, Yue, et al.
Publicado: (2021)

Sam68 promotes hepatic gluconeogenesis via CRTC2
por: Qiao, Aijun, et al.
Publicado: (2021)

CREB5 promotes invasiveness and metastasis in colorectal cancer by directly activating MET
por: Wang, Shuyang, et al.
Publicado: (2020)

Phosphorylation of CAP1 regulates lung cancer proliferation, migration, and invasion
por: Zeng, Jie, et al.
Publicado: (2021)

Novel role for the CRTC2 in lipid homeostasis
por: Matsuzaka, Takashi, et al.
Publicado: (2016)

The HBx–CTTN interaction promotes cell proliferation and migration of hepatocellular carcinoma via CREB1
por: Li, Yajun, et al.
Publicado: (2019)

Overexpression of NELFCD promotes colorectal cancer cells proliferation, migration, and invasion
por: Song, Shenglei, et al.
Publicado: (2018)

Sauchinone inhibits the proliferation, migration and invasion of breast cancer cells by suppressing Akt-CREB-MMP13 signaling pathway
por: Kim, Na Hui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_nf6li2rdjavqs9vm6lu0gd4o4p