A Genetic Screen Links the Disease-Associated Nab2 RNA-Binding Protein to the Planar Cell Polarity Pathway in Drosophila melanogaster

Mutations in the gene encoding the ubiquitously expressed RNA-binding protein ZC3H14 result in a non-syndromic form of autosomal recessive intellectual disability in humans. Studies in Drosophila have defined roles for the ZC3H14 ortholog, Nab2 (aka Drosophila Nab2 or dNab2), in axon guidance and me...

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Detalles Bibliográficos
Autores principales: Lee, Wei-Hsuan, Corgiat, Edwin, Rounds, J. Christopher, Shepherd, Zenyth, Corbett, Anita H., Moberg, Kenneth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Mutant Screen Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534439/
https://www.ncbi.nlm.nih.gov/pubmed/32817074
http://dx.doi.org/10.1534/g3.120.401637

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