Cargando…

An enzymatic Alder-ene reaction

An ongoing challenge in chemical research is to design catalysts that select the outcomes of the reactions of complex molecules. Chemists rely on organo- or transition metal catalysts to control stereo-, regio-, and periselectivity (selectivity among possible pericyclic reactions). Nature achieves t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ohashi, Masao, Jamieson, Cooper S., Cai, Yujuan, Tan, Dan, Kanayama, Daiki, Tang, Man-cheng, Anthony, Sarah M., Chari, Jason V., Barber, Joyann S., Picazo, Elias, Kakule, Thomas B., Cao, Shugeng, Garg, Neil K., Zhou, Jiahai, Houk, K. N., Tang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534572/ https://www.ncbi.nlm.nih.gov/pubmed/32999480 http://dx.doi.org/10.1038/s41586-020-2743-5

Ejemplares similares

Structural Basis for Stereoselective Dehydration and Hydrogen-Bonding Catalysis by the SAM-Dependent Pericyclase LepI
por: Cai, Yujuan, et al.
Publicado: (2019)

Discovery and characterization of a terpene biosynthetic pathway featuring a norbornene-forming Diels-Alderase
por: Sun, Zuodong, et al.
Publicado: (2022)

Diastereoselectivity on Intramolecular Alder‐ene Reaction of 1,6‐Dienes
por: de Cózar, Abel
Publicado: (2022)

A Molecular Electron Density Theory Study of the Competitiveness of Polar Diels–Alder and Polar Alder-ene Reactions
por: Domingo, Luis R., et al.
Publicado: (2018)

Efficient Heterogeneous Copper-Catalyzed Alder-Ene Reaction of Allenynamides to Pyrrolines
por: Zheng, Zhiyao, et al.
Publicado: (2022)

Rhodium-catalyzed intermolecular enantioselective Alder–ene type reaction of cyclopentenes with silylacetylenes
por: Zhang, Dongquan, et al.
Publicado: (2021)

Biosynthesis of the fungal glyceraldehyde-3-phosphate dehydrogenase inhibitor heptelidic acid and mechanism of self-resistance
por: Yan, Yan, et al.
Publicado: (2020)

Diels–Alder Reactions of Allene with Benzene and Butadiene: Concerted, Stepwise, and Ambimodal Transition States
por: Pham, Hung V., et al.
Publicado: (2014)

Secondary Orbital Interactions Enhance the Reactivity of Alkynes in Diels–Alder Cycloadditions
por: Levandowski, Brian J., et al.
Publicado: (2019)

Alder-ene reactions driven by high steric strain and bond angle distortion to form benzocyclobutenes
por: Gupta, Saswata, et al.
Publicado: (2018)

DFT Modeling of the Alternating Radical Copolymerization and Alder-Ene Reaction between Maleic Anhydride and Olefins
por: Nifant’ev, Ilya, et al.
Publicado: (2020)

Peroxidase-induced C–N bond formation via nitroso ene and Diels–Alder reactions
por: Jäger, Christina, et al.
Publicado: (2023)

Thiol–ene photoimmobilization of chymotrypsin on polysiloxane gels for enzymatic peptide synthesis
por: Wang, Meng, et al.
Publicado: (2018)

Correction to “Secondary Orbital Interactions Enhance the Reactivity of Alkynes in Diels–Alder Cycloadditions”
por: Levandowski, Brian J., et al.
Publicado: (2019)

Alginate based antimicrobial hydrogels formed by integrating Diels–Alder “click chemistry” and the thiol–ene reaction
por: Wang, Gang, et al.
Publicado: (2018)

Intramolecular Diels–Alder Reactions of Cycloalkenones: Stereoselectivity, Lewis Acid Acceleration, and Halogen Substituent Effects
por: Pham, Hung V., et al.
Publicado: (2014)

Electric field–catalyzed single-molecule Diels-Alder reaction dynamics
por: Yang, Chen, et al.
Publicado: (2021)

Enantio- and Diastereoenriched Enzymatic Synthesis of 1,2,3-Polysubstituted Cyclopropanes from (Z/E)-Trisubstituted Enol Acetates
por: Mao, Runze, et al.
Publicado: (2023)

The pentadehydro-Diels–Alder reaction
por: Wang, Teng, et al.
Publicado: (2016)

Aerobic C−N Bond Formation through Enzymatic Nitroso‐Ene‐Type Reactions
por: Jäger, Christina, et al.
Publicado: (2023)

Enzymatic one-step ring contraction for quinolone biosynthesis
por: Kishimoto, Shinji, et al.
Publicado: (2018)

The hexadehydro-Diels–Alder reaction
por: Hoye, Thomas R., et al.
Publicado: (2012)

Mr. Alder, on Contagion and Fever
por: Alder, Thomas
Publicado: (1807)

Dr. Alder, on Contagion and Fever
por: Alder, Thomas
Publicado: (1807)

An on‐surface Diels–Alder reaction
por: Castro‐Esteban, Jesús, et al.
Publicado: (2021)

Dual Activation of Aromatic Diels–Alder Reactions
por: Narsaria, Ayush K., et al.
Publicado: (2019)

SAM-Dependent Enzyme-Catalysed Pericyclic Reactions in Natural Product Biosynthesis
por: Ohashi, Masao, et al.
Publicado: (2017)

Mulberry Diels–Alder-type adducts: isolation, structure, bioactivity, and synthesis
por: Luo, Si-Yuan, et al.
Publicado: (2022)

Generation of novel Diels–Alder reactions using a generative adversarial network
por: Li, Sheng, et al.
Publicado: (2022)

Cross-Linking of Polypropylene via the Diels–Alder Reaction
por: Muljana, Henky, et al.
Publicado: (2022)

Mr. Alder, on the Disordered States of the Lungs
por: Alder, Thomas
Publicado: (1804)

Dr. Alder, on Quarantines, Contagion, and Fevers
por: Alder, Thomas
Publicado: (1808)

Dr. Alder, on Quarantines, Contagion, and Fevers
por: Alder, Thomas
Publicado: (1808)

Mr. Alder, in Answer to Dr. Brown
por: Alder, Tho.
Publicado: (1806)

Dr. Alder, on Quarantines, Contagion, and Fever
por: Alder, Thomas
Publicado: (1807)

Origin of asynchronicity in Diels–Alder reactions
por: Vermeeren, Pascal, et al.
Publicado: (2021)

The Effect of Different Moderate Thermal Modification Durations on the Wood Properties of American Alder
por: Liu, Honghai, et al.
Publicado: (2022)

An MM and QM Study of Biomimetic Catalysis of Diels-Alder Reactions Using Cyclodextrins
por: Chen, Wei, et al.
Publicado: (2018)

Vinylazaarenes as dienophiles in Lewis acid-promoted Diels–Alder reactions
por: Davis, Anna E., et al.
Publicado: (2021)

Diels–Alder reactions in confined spaces: the influence of catalyst structure and the nature of active sites for the retro-Diels–Alder reaction
por: Cantín, Ángel, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_vsvcbb38qtehduq9hm4d306cjj