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G‐Quadruplexes act as sequence‐dependent protein chaperones

Maintaining proteome health is important for cell survival. Nucleic acids possess the ability to prevent protein aggregation more efficiently than traditional chaperone proteins. In this study, we explore the sequence specificity of the chaperone activity of nucleic acids. Evaluating over 500 nuclei...

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Detalles Bibliográficos
Autores principales: Begeman, Adam, Son, Ahyun, Litberg, Theodore J, Wroblewski, Tadeusz H, Gehring, Thane, Huizar Cabral, Veronica, Bourne, Jennifer, Xuan, Zhenyu, Horowitz, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534610/
https://www.ncbi.nlm.nih.gov/pubmed/32945124
http://dx.doi.org/10.15252/embr.201949735