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Structures and dynamics of the novel S1/S2 protease cleavage site loop of the SARS-CoV-2 spike glycoprotein

At the end of 2019, a new highly virulent coronavirus known under the name SARS-CoV-2 emerged as a human pathogen. One key feature of SARS-CoV-2 is the presence of an enigmatic insertion in the spike glycoprotein gene representing a novel multibasic S1/S2 protease cleavage site. The proteolytic clea...

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Detalles Bibliográficos
Autores principales:	Lemmin, Thomas, Kalbermatter, David, Harder, Daniel, Plattet, Philippe, Fotiadis, Dimitrios
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534663/ https://www.ncbi.nlm.nih.gov/pubmed/33043289 http://dx.doi.org/10.1016/j.yjsbx.2020.100038

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