Risk of immunotherapy-related narcolepsy in genetically predisposed patients: a case report of narcolepsy after administration of pembrolizumab

BACKGROUND: Immune-related adverse events associated with immune checkpoint therapy cause autoimmune disease-like symptoms. People who carry specific genotypes or haplotypes of human leucocyte antigen (HLA) are known to be predisposed to develop autoimmune diseases including narcolepsy. Immunotherap...

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Detalles Bibliográficos
Autores principales: Natori, Yutaka, Sasaki, Eisaku, Soeda, Shu, Furukawa, Shigenori, Azami, Yusuke, Tokuda, Emi, Kanbayashi, Takashi, Saji, Shigehira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534705/
https://www.ncbi.nlm.nih.gov/pubmed/33004543
http://dx.doi.org/10.1136/jitc-2020-001164

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