Nociceptors protect sickle cell disease mice from vaso-occlusive episodes and chronic organ damage

Sickle cell disease (SCD) is a common hereditary hematologic disorder. SCD patients suffer from acute vaso-occlusive episodes (VOEs), chronic organ damage, and premature death, with few therapeutic options. Although severe pain is a major clinical manifestation of SCD, it remains unknown whether noc...

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Detalles Bibliográficos
Autores principales: Xu, Chunliang, Gulinello, Maria, Frenette, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534906/
https://www.ncbi.nlm.nih.gov/pubmed/33045060
http://dx.doi.org/10.1084/jem.20200065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534906/
https://www.ncbi.nlm.nih.gov/pubmed/33045060
http://dx.doi.org/10.1084/jem.20200065

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