Quality control of 40S ribosome head assembly ensures scanning competence

During translation initiation, 40S ribosomes scan the mRNA until they encounter the start codon, where conformational changes produce a translation-competent 80S complex. Destabilizing the scanning complex results in misinitiation at non-AUG codons, demonstrating its importance for fidelity. Here, w...

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Detalles Bibliográficos
Autores principales: Huang, Haina, Ghalei, Homa, Karbstein, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534925/
https://www.ncbi.nlm.nih.gov/pubmed/33007085
http://dx.doi.org/10.1083/jcb.202004161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534925/
https://www.ncbi.nlm.nih.gov/pubmed/33007085
http://dx.doi.org/10.1083/jcb.202004161

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