Flavonoid glycosides and their putative human metabolites as potential inhibitors of the SARS-CoV-2 main protease (Mpro) and RNA-dependent RNA polymerase (RdRp)

BACKGROUND: Since the World Health Organization (WHO) declared Coronavirus disease 2019 (COVID-19) to be a pandemic infection, important severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural proteins (nsp) have been analysed as promising targets in virtual screening approaches....

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Detalles Bibliográficos
Autores principales: da Silva, Felipe Moura A, da Silva, Katia Pacheco A, de Oliveira, Luiz Paulo M, Costa, Emmanoel V, Koolen, Hector HF, Pinheiro, Maria Lúcia B, de Souza, Antonia Queiroz L, de Souza, Afonso Duarte L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534957/
https://www.ncbi.nlm.nih.gov/pubmed/33027419
http://dx.doi.org/10.1590/0074-02760200207

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