Mechanisms and therapeutic implications of RTA 408, an activator of Nrf2, in subarachnoid hemorrhage–induced delayed cerebral vasospasm and secondary brain injury

OBJECTIVES: More and more evidence suggests oxidative stress and inflammation contribute importantly to subarachnoid hemorrhage (SAH)-induced cerebral vasospasm and secondary brain injury. Recent evidence indicates Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) increases the expression of antiox...

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Detalles Bibliográficos
Autores principales: Tsai, Tai-Hsin, Lin, Szu-Huai, Wu, Chieh-Hsin, Tsai, Yi-Cheng, Yang, Sheau-Fang, Lin, Chih-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535038/
https://www.ncbi.nlm.nih.gov/pubmed/33017422
http://dx.doi.org/10.1371/journal.pone.0240122

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