The Advances of Ceria Nanoparticles for Biomedical Applications in Orthopaedics

The ongoing biomedical nanotechnology has intrigued increasingly intense interests in cerium oxide nanoparticles, ceria nanoparticles or nano-ceria (CeO(2)-NPs). Their remarkable vacancy-oxygen defect (VO) facilitates the redox process and catalytic activity. The verification has illustrated that Ce...

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Autores principales: Li, Hongru, Xia, Peng, Pan, Su, Qi, Zhiping, Fu, Chuan, Yu, Ziyuan, Kong, Weijian, Chang, Yuxin, Wang, Kai, Wu, Dankai, Yang, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535115/
https://www.ncbi.nlm.nih.gov/pubmed/33061376
http://dx.doi.org/10.2147/IJN.S270229
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author Li, Hongru
Xia, Peng
Pan, Su
Qi, Zhiping
Fu, Chuan
Yu, Ziyuan
Kong, Weijian
Chang, Yuxin
Wang, Kai
Wu, Dankai
Yang, Xiaoyu
author_facet Li, Hongru
Xia, Peng
Pan, Su
Qi, Zhiping
Fu, Chuan
Yu, Ziyuan
Kong, Weijian
Chang, Yuxin
Wang, Kai
Wu, Dankai
Yang, Xiaoyu
author_sort Li, Hongru
collection PubMed
description The ongoing biomedical nanotechnology has intrigued increasingly intense interests in cerium oxide nanoparticles, ceria nanoparticles or nano-ceria (CeO(2)-NPs). Their remarkable vacancy-oxygen defect (VO) facilitates the redox process and catalytic activity. The verification has illustrated that CeO(2)-NPs, a nanozyme based on inorganic nanoparticles, can achieve the anti-inflammatory effect, cancer resistance, and angiogenesis. Also, they can well complement other materials in tissue engineering (TE). Pertinent to the properties of CeO(2)-NPs and the pragmatic biosynthesis methods, this review will emphasize the recent application of CeO(2)-NPs to orthopedic biomedicine, in particular, the bone tissue engineering (BTE). The presentation, assessment, and outlook of the orthopedic potential and shortcomings of CeO(2)-NPs in this review expect to provide reference values for the future research and development of therapeutic agents based on CeO(2)-NPs.
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spelling pubmed-75351152020-10-14 The Advances of Ceria Nanoparticles for Biomedical Applications in Orthopaedics Li, Hongru Xia, Peng Pan, Su Qi, Zhiping Fu, Chuan Yu, Ziyuan Kong, Weijian Chang, Yuxin Wang, Kai Wu, Dankai Yang, Xiaoyu Int J Nanomedicine Review The ongoing biomedical nanotechnology has intrigued increasingly intense interests in cerium oxide nanoparticles, ceria nanoparticles or nano-ceria (CeO(2)-NPs). Their remarkable vacancy-oxygen defect (VO) facilitates the redox process and catalytic activity. The verification has illustrated that CeO(2)-NPs, a nanozyme based on inorganic nanoparticles, can achieve the anti-inflammatory effect, cancer resistance, and angiogenesis. Also, they can well complement other materials in tissue engineering (TE). Pertinent to the properties of CeO(2)-NPs and the pragmatic biosynthesis methods, this review will emphasize the recent application of CeO(2)-NPs to orthopedic biomedicine, in particular, the bone tissue engineering (BTE). The presentation, assessment, and outlook of the orthopedic potential and shortcomings of CeO(2)-NPs in this review expect to provide reference values for the future research and development of therapeutic agents based on CeO(2)-NPs. Dove 2020-09-29 /pmc/articles/PMC7535115/ /pubmed/33061376 http://dx.doi.org/10.2147/IJN.S270229 Text en © 2020 Li et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Li, Hongru
Xia, Peng
Pan, Su
Qi, Zhiping
Fu, Chuan
Yu, Ziyuan
Kong, Weijian
Chang, Yuxin
Wang, Kai
Wu, Dankai
Yang, Xiaoyu
The Advances of Ceria Nanoparticles for Biomedical Applications in Orthopaedics
title The Advances of Ceria Nanoparticles for Biomedical Applications in Orthopaedics
title_full The Advances of Ceria Nanoparticles for Biomedical Applications in Orthopaedics
title_fullStr The Advances of Ceria Nanoparticles for Biomedical Applications in Orthopaedics
title_full_unstemmed The Advances of Ceria Nanoparticles for Biomedical Applications in Orthopaedics
title_short The Advances of Ceria Nanoparticles for Biomedical Applications in Orthopaedics
title_sort advances of ceria nanoparticles for biomedical applications in orthopaedics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535115/
https://www.ncbi.nlm.nih.gov/pubmed/33061376
http://dx.doi.org/10.2147/IJN.S270229
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