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Establishment of a diagnostic model of coronary heart disease for patients with diabetic foot

This study aims to establish a diagnostic model of coronary heart disease (CHD) for diabetic foot (DF) patients. The clinical data of 489 hospitalized patients with DF were retrospectively analyzed in this case-control study. The patients were divided into the CHD group (DF with CHD, n = 212) and th...

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Autores principales: Chen, Ying, Meng, Liwei, Wang, Liangchen, Xiao, Li, Yang, Caizhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535636/
https://www.ncbi.nlm.nih.gov/pubmed/33019409
http://dx.doi.org/10.1097/MD.0000000000022334
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author Chen, Ying
Meng, Liwei
Wang, Liangchen
Xiao, Li
Yang, Caizhe
author_facet Chen, Ying
Meng, Liwei
Wang, Liangchen
Xiao, Li
Yang, Caizhe
author_sort Chen, Ying
collection PubMed
description This study aims to establish a diagnostic model of coronary heart disease (CHD) for diabetic foot (DF) patients. The clinical data of 489 hospitalized patients with DF were retrospectively analyzed in this case-control study. The patients were divided into the CHD group (DF with CHD, n = 212) and the control group (DF without CHD, n = 277). Univariate analysis was performed to screen for CHD-related risk factors, and multivariate logistic regression analysis was conducted to determine significant CHD risk factors. Scores were assigned according to the ratio of risk factors (OR) to establish a diagnostic model of CHD for patients with DF. The area under the ROC curve was used to test the application value of the diagnostic model. The logistic regression analysis showed that the risk factors for CHD in DF patients were age, duration of diabetes, toe-brachial index, hyperuricemia, and chronic renal insufficiency. The area under the ROC curve of the diagnostic model was 0.798 (0.759–0.837), the diagnostic point of CHD was 6 points, the diagnostic sensitivity was 69.3%, and the specificity was 76.5%. The established model has good diagnostic value and provides the basis for preliminary screening for CHD in patients with DF.
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spelling pubmed-75356362020-10-14 Establishment of a diagnostic model of coronary heart disease for patients with diabetic foot Chen, Ying Meng, Liwei Wang, Liangchen Xiao, Li Yang, Caizhe Medicine (Baltimore) 4300 This study aims to establish a diagnostic model of coronary heart disease (CHD) for diabetic foot (DF) patients. The clinical data of 489 hospitalized patients with DF were retrospectively analyzed in this case-control study. The patients were divided into the CHD group (DF with CHD, n = 212) and the control group (DF without CHD, n = 277). Univariate analysis was performed to screen for CHD-related risk factors, and multivariate logistic regression analysis was conducted to determine significant CHD risk factors. Scores were assigned according to the ratio of risk factors (OR) to establish a diagnostic model of CHD for patients with DF. The area under the ROC curve was used to test the application value of the diagnostic model. The logistic regression analysis showed that the risk factors for CHD in DF patients were age, duration of diabetes, toe-brachial index, hyperuricemia, and chronic renal insufficiency. The area under the ROC curve of the diagnostic model was 0.798 (0.759–0.837), the diagnostic point of CHD was 6 points, the diagnostic sensitivity was 69.3%, and the specificity was 76.5%. The established model has good diagnostic value and provides the basis for preliminary screening for CHD in patients with DF. Lippincott Williams & Wilkins 2020-10-02 /pmc/articles/PMC7535636/ /pubmed/33019409 http://dx.doi.org/10.1097/MD.0000000000022334 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 4300
Chen, Ying
Meng, Liwei
Wang, Liangchen
Xiao, Li
Yang, Caizhe
Establishment of a diagnostic model of coronary heart disease for patients with diabetic foot
title Establishment of a diagnostic model of coronary heart disease for patients with diabetic foot
title_full Establishment of a diagnostic model of coronary heart disease for patients with diabetic foot
title_fullStr Establishment of a diagnostic model of coronary heart disease for patients with diabetic foot
title_full_unstemmed Establishment of a diagnostic model of coronary heart disease for patients with diabetic foot
title_short Establishment of a diagnostic model of coronary heart disease for patients with diabetic foot
title_sort establishment of a diagnostic model of coronary heart disease for patients with diabetic foot
topic 4300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535636/
https://www.ncbi.nlm.nih.gov/pubmed/33019409
http://dx.doi.org/10.1097/MD.0000000000022334
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