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A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer

The dependency of cancer cells on glutamine may be exploited therapeutically as a new strategy for treating cancers that lack druggable driver genes. Here we found that human liver cancer was dependent on extracellular glutamine. However, targeting glutamine addiction using the glutaminase inhibitor...

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Detalles Bibliográficos
Autores principales:	Jin, Haojie, Wang, Siying, Zaal, Esther A, Wang, Cun, Wu, Haiqiu, Bosma, Astrid, Jochems, Fleur, Isima, Nikita, Jin, Guangzhi, Lieftink, Cor, Beijersbergen, Roderick, Berkers, Celia R, Qin, Wenxin, Bernards, Rene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535927/ https://www.ncbi.nlm.nih.gov/pubmed/33016874 http://dx.doi.org/10.7554/eLife.56749

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