m6A RNA methylation impacts fate choices during skin morphogenesis

N(6)-methyladenosine is the most prominent RNA modification in mammals. Here, we study mouse skin embryogenesis to tackle m6A’s functions and physiological importance. We first landscape the m6A modifications on skin epithelial progenitor mRNAs. Contrasting with in vivo ribosomal profiling, we unear...

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Detalles Bibliográficos
Autores principales: Xi, Linghe, Carroll, Thomas, Matos, Irina, Luo, Ji-Dung, Polak, Lisa, Pasolli, H Amalia, Jaffrey, Samie R, Fuchs, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535931/
https://www.ncbi.nlm.nih.gov/pubmed/32845239
http://dx.doi.org/10.7554/eLife.56980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535931/
https://www.ncbi.nlm.nih.gov/pubmed/32845239
http://dx.doi.org/10.7554/eLife.56980

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