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m6A RNA methylation impacts fate choices during skin morphogenesis
N(6)-methyladenosine is the most prominent RNA modification in mammals. Here, we study mouse skin embryogenesis to tackle m6A’s functions and physiological importance. We first landscape the m6A modifications on skin epithelial progenitor mRNAs. Contrasting with in vivo ribosomal profiling, we unear...
Autores principales: | Xi, Linghe, Carroll, Thomas, Matos, Irina, Luo, Ji-Dung, Polak, Lisa, Pasolli, H Amalia, Jaffrey, Samie R, Fuchs, Elaine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535931/ https://www.ncbi.nlm.nih.gov/pubmed/32845239 http://dx.doi.org/10.7554/eLife.56980 |
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