Left Bundle Branch Block: A Reversible Pernicious Effect of Lacosamide

A 95-year-old male with a medical history of focal epilepsy presented with transient ischemic attack (TIA)/pre-syncope like symptoms. He was on lacosamide (LCM) and levetiracetam. On evaluation, he was found to have left bundle branch block (LBBB), sinus pause of three seconds, and 1st degree atriov...

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Autores principales: Majmundar, Monil M, Kansara, Tikal, Shah, Palak, Zala, Harshvardhan, Chaudhari, Shobhana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Cardiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535942/
https://www.ncbi.nlm.nih.gov/pubmed/33042675
http://dx.doi.org/10.7759/cureus.10234
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author Majmundar, Monil M
Kansara, Tikal
Shah, Palak
Zala, Harshvardhan
Chaudhari, Shobhana
author_facet Majmundar, Monil M
Kansara, Tikal
Shah, Palak
Zala, Harshvardhan
Chaudhari, Shobhana
author_sort Majmundar, Monil M
collection PubMed
description A 95-year-old male with a medical history of focal epilepsy presented with transient ischemic attack (TIA)/pre-syncope like symptoms. He was on lacosamide (LCM) and levetiracetam. On evaluation, he was found to have left bundle branch block (LBBB), sinus pause of three seconds, and 1st degree atrioventricular (AV) block. After holding LCM, electrocardiogram changes were reversed to baseline (before commencing LCM). In conclusion, to the best of our knowledge, this is the first case of reversible LBBB along with sinoatrial (SA) node and AV node dysfunction in an elderly male on LCM therapy.
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spelling pubmed-75359422020-10-08 Left Bundle Branch Block: A Reversible Pernicious Effect of Lacosamide Majmundar, Monil M Kansara, Tikal Shah, Palak Zala, Harshvardhan Chaudhari, Shobhana Cureus Cardiology A 95-year-old male with a medical history of focal epilepsy presented with transient ischemic attack (TIA)/pre-syncope like symptoms. He was on lacosamide (LCM) and levetiracetam. On evaluation, he was found to have left bundle branch block (LBBB), sinus pause of three seconds, and 1st degree atrioventricular (AV) block. After holding LCM, electrocardiogram changes were reversed to baseline (before commencing LCM). In conclusion, to the best of our knowledge, this is the first case of reversible LBBB along with sinoatrial (SA) node and AV node dysfunction in an elderly male on LCM therapy. Cureus 2020-09-03 /pmc/articles/PMC7535942/ /pubmed/33042675 http://dx.doi.org/10.7759/cureus.10234 Text en Copyright © 2020, Majmundar et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Majmundar, Monil M
Kansara, Tikal
Shah, Palak
Zala, Harshvardhan
Chaudhari, Shobhana
Left Bundle Branch Block: A Reversible Pernicious Effect of Lacosamide
title Left Bundle Branch Block: A Reversible Pernicious Effect of Lacosamide
title_full Left Bundle Branch Block: A Reversible Pernicious Effect of Lacosamide
title_fullStr Left Bundle Branch Block: A Reversible Pernicious Effect of Lacosamide
title_full_unstemmed Left Bundle Branch Block: A Reversible Pernicious Effect of Lacosamide
title_short Left Bundle Branch Block: A Reversible Pernicious Effect of Lacosamide
title_sort left bundle branch block: a reversible pernicious effect of lacosamide
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535942/
https://www.ncbi.nlm.nih.gov/pubmed/33042675
http://dx.doi.org/10.7759/cureus.10234
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AT zalaharshvardhan leftbundlebranchblockareversibleperniciouseffectoflacosamide
AT chaudharishobhana leftbundlebranchblockareversibleperniciouseffectoflacosamide

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